Pennsylvania Route 841 is a state highway in Chester County, Pennsylvania. The route runs from the Maryland border in the community of Lewisville in Elk Township, where the road continues as Maryland Route 213, north to PA 82 in the community of Doe Run in West Marlborough Township. The route heads through rural areas of southwestern Chester County on a two-lane undivided road. PA 841 passes through West Grove, where it has an interchange with U.S. Route 1. PA 841 was first assigned to an unpaved road running from Springdell to PA 82 in 1928. The route was extended south to its current terminus in 1937 and was completely paved by 1940.

Chester County, colloquially referred to as Chesco, is a county in the Commonwealth of Pennsylvania. It is located in the Delaware Valley region, located in the southeastern part of the state. As of the 2020 census, the population was 545,823(As of 2022), increasing by 7.1% from 498,886 in 2010. The county seat is the Borough of West Chester. The most populous of its 73 municipalities is Tredyffrin Township. The most populous boroughs are West Chester and Phoenixville. Coatesville is the only municipality in the County organized under the City form of government, a technical rather than demographic distinction. Chester County was one of the three original Pennsylvania counties created by William Penn in 1682. It was named for Chester, England. The county is part of the Southeast Pennsylvania region of the state.