Persephone "Penny" Valentine is a fictional character from the BBC medical drama television series Holby City, portrayed by actress Emma Catherwood. She appeared from 2009–2011, in the programme's eleventh to thirteenth series. Penny was introduced alongside her younger brother, Oliver, as a Foundation House Officer 1 (F1) on surgical rotation at Holby City Hospital. She eventually progressed to F2 level, before being killed off in the aftermath of a train crash; her death occurring off-screen.

The thirteenth series of the British medical drama television series Holby City began airing in the United Kingdom on BBC One on 19 October 2010, and ran for 52 episodes, concluding on 11 October 2011.