Peoria High School is a public high school in Peoria, Illinois. Peoria High School was established in 1856 and is the second oldest continually operating high school west of the Allegheny Mountains after Evansville Central High School in Indiana. Peoria High is located at 1615 N. North Street and moved to this location in 1916. Peoria High School is commonly referred to as "Central" to distinguish it from Richwoods and Manual, and it is centrally located in Peoria. Peoria is the only city in the Peoria metro area with multiple high schools. The motto is the "Pride of the City".

Debora Green is an American physician who pleaded no contest to setting a 1995 fire that burned down her family's home and killed two of her children, and to poisoning her husband with ricin with the intention of causing his death. The case was sensational, and covered heavily by news media, especially in the Kansas–Missouri area, where the crimes occurred. Though Green has petitioned for a new trial twice in recent years, her requests have not been successful.