Perrysville is a village in Ashland County, Ohio, United States. The population was 729 at the 2020 census.

Ashland County is a county located in the northeastern portion of the U.S. state of Ohio. As of the 2020 census, the population was 52,447. Its county seat and largest city is Ashland. The county is named for "Ashland", the home of Senator Henry Clay near Lexington, Kentucky. It was formed in 1846 from parts of Huron, Lorain, Richland and Wayne Counties.