Pesaro is a comune (municipality) in the Italian region of Marche, capital of the province of Pesaro and Urbino, on the Adriatic Sea. According to the 2011 census, its population was 95,011, making it the second most populous city in the Marche, after Ancona. Pesaro was dubbed the "Cycling City" by the Italian environmentalist association Legambiente in recognition of its extensive network of bicycle paths and promotion of cycling. It is also known as "City of Music", for it is the birthplace of the composer Gioachino Rossini. In 2015 the Italian Government applied for Pesaro to be declared a "Creative City" in UNESCO's World Heritage Sites. In 2017 Pesaro received the European City of Sport award together with Aosta, Cagliari and Vicenza.

The Via Flaminia was an ancient Roman road leading from Rome over the Apennine Mountains to Ariminum (Rimini) on the coast of the Adriatic Sea, and due to the ruggedness of the mountains was the major option the Romans had for travel between Etruria, Latium, Campania, and the Po Valley. The section running through northern Rome is where Constantine the Great, allegedly, had his famous vision of the Chi Rho, leading to his conversion to Christianity and the Christianization of the Roman Empire.