Peter Löwenbräu Griffin Sr. is a fictional character and the protagonist of the American animated sitcom Family Guy. He is voiced by the series' creator, Seth MacFarlane, and first appeared on television, along with the rest of the Griffin family, in the episode "Death Has a Shadow" on January 31, 1999. Peter was created and designed by MacFarlane himself. MacFarlane was asked to pitch a pilot to the Fox Broadcasting Company based on Larry & Steve, a short made by MacFarlane which featured a middle-aged character named Larry and an intellectual dog, Steve. For the series, Larry was renamed Peter.

Lois Patrice Griffin is a fictional character from the animated television series Family Guy. She is voiced by Alex Borstein and first appeared on television, along with the rest of the Griffin family, in the episode "Death Has a Shadow" on January 31, 1999. Lois was originally created and designed by series creator Seth MacFarlane for a student film called The Life of Larry in 1995.