Phraya Manopakorn Nitithada was the first Prime Minister of Siam after the Siamese Revolution of 1932 as he was selected by the leader of the People's Party – the party that instigated the revolution. However, in the following year, Manoparkorn was ousted by a coup in 1933 due to the conflicts between members of People's Party.

The prime minister of Thailand is the head of government of Thailand. The prime minister is also the chair of the Cabinet of Thailand. The post has existed since the Revolution of 1932, when the country became a constitutional monarchy. Prior to the 2014 coup d'état, the prime minister was nominated by a vote in the Thai House of Representatives by a simple majority, and is then appointed and sworn in by the king of Thailand. The house's selection is usually based on the fact that either the prime minister is the leader of the largest political party in the lower house or the leader of the largest coalition of parties. In accordance with the 2017 Constitution, the Prime Minister can hold the office for no longer than eight years, consecutively or not. The post of Prime Minister is currently held by Pheu Thai Party politician and former CEO of Sansiri, Srettha Thavisin.