The Piano Concerto No. 2 was written by American composer Philip Glass in 2004. It is also called the Piano Concerto No. 2: After Lewis and Clark, due to its musical representation of the American pioneers. It was composed for the Nebraska Lewis and Clark Bicentennial Commission, the Lied Center for Performing Arts, and the University of Nebraska-Lincoln Hixson–Lied College of Fine and Performing Arts. It is included as one of the concerti in Glass' Concerto Project, a four-volume collection of commissioned works. The work itself deals with the journey of Meriwether Lewis and William Clark, interpreting the stages of their expedition progressively in each movement.

The Concerto Project is a collection of concerti written by Philip Glass. The series was begun in 2000 and contains eight works, the most famous of which is probably the Concerto for Cello and Orchestra. Some of the concerti in the volumes were written before the commencement of the project and were categorized into the series.