The Pico Cão Grande is a landmark needle-shaped volcanic plug peak in São Tomé and Príncipe, in the Caué District of São Tomé Island in Parque Natural Obô de São Tomé. Its summit is 663 m (2,175 ft) above sea level, and it rises about 370 m (1,210 ft) over the surrounding terrain. The volcanic plug was formed by magma solidifying in the vent of an active volcano. The nearest village is Vila Clotilde, 3 km to the east. The district seat São João dos Angolares is 9 km to the east.

São Tomé and Príncipe, officially the Democratic Republic of São Tomé and Príncipe, is an island country in the Gulf of Guinea, the western equatorial coast of Central Africa.