Pierre Ngendandumwe was a Burundian politician. He was a member of the Union for National Progress and was an ethnic Hutu. On 18 June 1963, about a year after Burundi gained independence and amidst efforts to bring about political cooperation between Hutus and the dominant minority Tutsis, Ngendandumwe became Burundi's first Hutu prime minister. He served as prime minister until 6 April 1964 and then became prime minister again on 7 January 1965, serving until his death. Eight days after beginning his second term, he was assassinated by a Rwandan Tutsi refugee.

Burundi, officially the Republic of Burundi, is a landlocked country in the Great Rift Valley at the junction between the African Great Lakes region and East Africa. It is bordered by Rwanda to the north, Tanzania to the east and southeast, and the Democratic Republic of the Congo to the west; Lake Tanganyika lies along its southwestern border. The capital cities are Gitega and Bujumbura, the latter being the country's largest city.