Pine Valley is a community and census-designated place (CDP) in the Cuyamaca Mountains of the Mountain Empire area, in southeastern San Diego County, California. The population was 1,510 at the 2010 census, up from 1,501 at the 2000 census.

The Pine Valley Creek Bridge, officially named the Nello Irwin Greer Memorial Bridge, is a reinforced concrete box girder bridge in San Diego County, California near the town of Pine Valley. The bridge was built in 1974 as part of the Interstate 8 (I-8) freeway system. At the time of its construction, it was the first bridge constructed in the United States using the segmental balanced cantilever method.