A pistol is a type of handgun, characterized by a barrel with an integral chamber. The word "pistol" is derived from the Middle French pistolet, meaning a small gun or knife, and first appeared in the English language c. 1570 when early handguns were produced in Europe. In colloquial usage, the word "pistol" is often used as a generic term to describe any type of handgun, inclusive of revolvers and the pocket-sized derringers.

A handgun is a firearm designed to be usable with only one hand. It is distinguished from a long gun which needs to be held by both hands and braced against the shoulder. Handguns have shorter effective ranges compared to long guns, and are much harder to shoot accurately. While most early handguns are single-shot pistols, the two most common types of handguns used in modern times are revolvers and semi-automatic pistols, although other handguns such as derringers and machine pistols also see infrequent usage.