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Pittsylvania County, Virginia

Pittsylvania County is a county located in the Commonwealth of Virginia. As of the 2010 census, the population was 63,506. Chatham is the county seat. Pittsylvania County is included in VA Micropolitan Statistical Area; the largest undeveloped uranium deposit in the United States is located in Pittsylvania County Originally "Pittsylvania" was a name suggested for an unrealized British colony to be located in what is now West Virginia. Pittsylvania County would not have been within this proposed colony, subsequently known as Vandalia; the county was formed in 1767 from Halifax County. It was named for William Pitt, 1st Earl of Chatham, who served as Prime Minister of Great Britain from 1766 to 1768 and opposed harsh colonial policies. In 1777 the western part of Pittsylvania County became Patrick Henry County. Maud Clement's History of Pittsylvania County notes the following: "Despite the settlers' intentions, towns failed to develop for two reasons: the low level of economic activity in the area and the competition from plantation settlements providing the kind of marketing and purchasing services offered by a town.

Plantation settlements along the rivers at ferrying points, became commercial centers. The most important for early Pittsylvania was that of Sam Pannill, a Scots-Irishman, who at the end of the eighteenth century, while still a young man, set up a plantation town at Green Hill on the north side of the Staunton River in Campbell County." "Its economy was reliant on a growing slave labor force. It was a county without a commercial center. Plantation villages on the major river thoroughfares were the only centers of trade, until the emergence of Danville." The city of Danville's history up through the antebellum period overall is an expression of the relationship between the town and the planters who influenced its development. According to the U. S. Census Bureau, the county has a total area of 978 square miles, of which 969 square miles is land and 9 square miles is water, it is the largest county in second-largest by total area. The county is bounded on the north by the Roanoke River, intersected by the Banister River through the center, drained by the Dan River on the south.

The county is divided into seven districts: Banister Callands-Gretna Chatham-Blairs Dan River Staunton River Tunstall Westover Virginia Counties Bedford County, Virginia - Northwest Campbell County, Virginia - North/Northeast Franklin County, Virginia - West/Northwest Halifax County, Virginia - East Henry County, Virginia - West/SouthwestVirginia Cities Danville, Virginia - SouthNorth Carolina Counties Caswell County, North Carolina - South/Southeast Rockingham County, North Carolina - South/Southwest US 29 US 58 US 311 US 360 SR 40 SR 41 SR 51 SR 57 SR 360 According to the most recent census records, there are 60,949 people, 26,687 households residing in the county. The population density was 65.5 people per square mile. There were 31,656 housing units at an average density of 32 per square mile; the racial makeup of the county was 76.20% White, 21.50% Black or African American, 0.30% Native American, 0.50% Asian, 0.37% from other races, 1.40% from two or more races. 2.70 % of the population were Latino of any race.

There were 26,687 households out. The average household size was 2.28 and the average family size was 2.93. The median income for a household in the county was $44,356; the per capita income for the county was $23,597. About 12.60% of the population were below the poverty line. Pittsylvania County is governed by an elected seven-member Board of Supervisors. Management of the County is vested in a Board-appointed County Administrator. There are five elected Constitutional Officers: Clerk of the Circuit Court: Mark Scarce Commonwealth's Attorney: Robert Bryan Haskins Sheriff: Michael "Mike" Taylor Commissioner of Revenue: Robin Coles-Goard Treasurer: Vincent Shorter Chatham Gretna Hurt Blairs Motley Mount Hermon Chatham Whittletown Woodlawn Woodlawn Heights List of Virginia counties National Register of Historic Places listings in Pittsylvania County, Virginia Uranium mining in the USA, Virginia Pittsylvania County Official Website WMDV TV44/Danville

Emily Pettit

Emily Pettit is an American poet and publisher from Northampton, Massachusetts. She has authored three books of poetry, she was shortlisted for The Believer Poetry award. She received her MFA in Poetry at University of Iowa and her BA in Contemporary Images at University of Massachusetts, Amherst, she teaches poetry at New York, New York. Pettit is an editor for Factory Hollow Press and notnostrums, publisher of the literary journal jubilat. Goat in the Snow was her first full-length collection of poetry and came out in early 2012, her second volume of poems, Blue Flame, appeared in 2019 from Carnegie Mellon University Press. Her work has been included in Huffington Post, Academy of American Poets, Vinyl Poetry, she has taught and/or lectured at Flying Object, University of Iowa, University of Massachusetts, Elms College. How What Happened to Limbo Goat in the Snow Official website

Conservative transposition

Transposition is the process by which a specific genetic sequence, known as a transposon, is moved from one location of the genome to another. Simple, or conservative transposition, is a non-replicative mode of transposition; that is, in conservative transposition the transposon is removed from the genome and reintegrated into a new, non-homologous locus, the same genetic sequence is conserved throughout the entire process. The site in which the transposon is reintegrated into the genome is called the target site. A target site can be within a different chromosome. Conservative transposition uses the "cut-and-paste" mechanism driven by the catalytic activity of the enzyme transposase. Transposase acts like DNA scissors. A simple, or conservative, transposon refers to the specific genetic sequence, moved via conservative transposition; these specific genetic sequences range in size, they can be hundreds to thousands of nucleotide base-pairs long. A transposon contains genetic sequences that encode for proteins that mediate its own movement, but can carry genes for additional proteins.

Transposase is encoded within the transposon DNA and used to facilitate its own movement, making this process self-sufficient within organisms. All simple transposons contain a transposase encoding region flanked by terminal inverted repeats, but the additional genes within the transposon DNA can vary. Viruses, for example, encode the essential viral transposase needed for conservative transposition as well as protective coat proteins that allow them to survive outside of cells, thus promoting the spread of mobile genetic elements; the mechanism by which conservative transposition occurs is called the "cut-and-paste" method, which involves five main steps: The transposase enzyme is bound to the inverted repeated sequences flanking the ends of the transposonInverted repeats define the ends of transposons and provide recognition sites for transposase to bind. The formation of the transposition complex In this step the DNA bends and folds into a pre-excision synaptic complex so the two transposases enzymes can interact.

The interaction of these transponases activates the complex. The transposase enzymes locate and bind to the target site within the target DNA. Transposase creates a double stranded break in the DNA and integrates the transposon into the target site. Both the excision and insertion of the transposon leaves single or double stranded gaps in the DNA, which are repaired by host enzymes such as DNA polymerase. Current researchers have developed gene transfer systems on the basis of conservative transposition which can integrate new DNA in both invertebrates and vertebrate genomes. Scientists alter the genetic sequence of a transposon in a laboratory setting insert this sequence into a vector, inserted into a target cell; the transposase coding region of these transposons is replaced by a gene of interest intended to be integrated into the genome. Conservative transposition is induced by the expression of transposase from another source within the cell, since the transposon no longer contains the transposase coding region to be self sufficient.

A second vector is prepared and inserted into the cell for expression of transposase. This technique is used in insertional mutagenesis research fields; the Sleeping Beauty transposon system is an example of gene transfer system developed for use in vertebrates. Further development in integration site preferences of transposable elements is expected to advance the technologies of human gene therapy

Nerariyum Nerathu

Nerariyum Nerathu is a 1985 Indian Malayalam-language feature film directed by Salaam Chembazhanthy for Sahrudaya Chithra starring Prem Nazir and Ratheesh in the lead roles, supported by T. G. Ravi and Rohini playing other important roles. Prem Nazir as Rajan Shankar as Rajeev Ratheesh as SI Mohan T. G. Ravi as Keshavankutty Unnimary as Thankamani Rohini as Rathi Jagathy Sreekumar as Kuttappan Bhagavathar/Kanishta Raja Kuthiravattam Pappu as Phalgunan Bindu Ghosh as Savithri Lalithasree as Vimala Menon Anuradha as Dancer C. I. Paul as Sadanandan Adoor Bhasi as Bhaskara Kurup Bahadoor as Gopala Pilla Master Madhuri as Sharada The music was composed by Johnson and the lyrics were written by Ezhacheri Ramachandran. Neerariyum Nerathu on IMDb

Ludwik Krzywicki

Ludwik Krzywicki was a Polish anthropologist and sociologist. One of the early champions of sociology in Poland, he approached historical materialism from a sociological viewpoint. From 1919 to 1936 he was a professor at the University of Warsaw. Ludwik Krzywicki was born at Płock in 1859 into an impoverished family. From an early age he showed an interest in psychology and natural sciences, studied the works of Darwin, Taine and Comte. Krzywicki studied mathematics at the University of Warsaw in Congress Poland. After obtaining his degree, he enrolled in the Faculty of Medicine but was expelled from the University on account of his political activities, he went abroad, first to Leipzig, Germany Zürich, in 1885 to Paris, where most of the Polish Socialist émigrés in Europe lived. It was in Paris that he began studying anthropology and ethnology. Krzywicki was one of the first scholars to research Lithuanian hill forts. Between 1900 and 1914 he conducted archeological digs in Samogitia and elsewhere and excavating fortress hills.

In 1908 he published Żmudż starożytnia, in which he sought to correlate his findings with chronicles that mentioned the castles and fortifications that he was investigating. In the same year he published an article entitled, W poszukiwaniu grodu Mendoga, dealing with where he believed the castle of King Mindaugas had been located. Krzywicki donated a large part of his findings to the Culture Museum in Kaunas, Lithuania, in 1939. One of his most important contributions was the theory of the migration of ideas: that ideas, which are created from and spread thanks to social needs and social expectations, can "migrate" to other places or times which have not yet been capable of expressing them autonomously; when that happens, if the new ideas succeed in embodying the needs and expectations encountered at the new place, they will take root and accelerate its socioeconomic development. Krzywicki continued his political activity; when the Italian Spiritualist Eusapia Palladino revisited Warsaw in the second half of May 1898, she held at least two séances in Krzywicki's apartment.

He was arrested many times, notably when he took part in the Revolution of 1905. During this period, he edited the paper of the Socialist Party, he finished a doctorate in Lvov with an ethnographic dissertation. Before World War I he lived in great hardship, but when the war broke out he was back in the front line of social activity, taking part in various workers' and trade union organizations though his relations with the Socialist Party had cooled. Krzywicki was one of the translators of Karl Marx's Das Kapital into Polish. After World War I he abandoned all political activity and focused on scientific research, intending to complete the works that he had never had the peace of mind or time to finish. However, he did take part in the management of scientific bodies, he served as vice-director of the Central Statistical Office, taught at the University of Warsaw and other institutions of higher education, directed the Socio-Economic Institute. During World War II he was injured during the defence of Warsaw in September 1939, the bomb that destroyed his apartment caused the loss of most of his papers and manuscripts.

His working conditions worsened and he died of heart disease in 1941. Meme Irena Krzywicka Central Statistical Office Eusapia Palladino List of Poles Krystyna Tokarzówna and Stanisław Fita, Bolesław Prus, 1847–1912: Kalendarz życia i twórczości, edited by Zygmunt Szweykowski, Warsaw, Państwowy Instytut Wydawniczy, 1969. Polish Philosophy page: Ludwik Krzywicki at the Wayback Machine

Julian Walsh

Julian Jrummi Walsh is a Jamaican-born Japanese track and field athlete competing in the sprints. He is the son of reggae drummer Emanuel Walsh, who married a Japanese woman and has lived in Japan for 20 years. Walsh grew up in Higashimurayama, he started running track in 10th grade, but his school had no facilities to practice on and no coach. He couldn't take track until the following year. After two seasons, he led off the Japanese silver medal winning relay team at the 2014 World Junior Championships in Athletics; that same summer he moved into senior level competition, anchoring the Asian-Pacific 4x400 metres relay team at the 2014 IAAF Continental Cup. Two years he qualified for the 2016 Olympics in the 400 metres, by running a 45.35 at the Japanese Olympic Trials in Nagoya at age 19. Julian Walsh at World Athletics Julian Walsh at JAAF Julian Walsh at the International Olympic Committee Julian Walsh at Olympics at Julian Walsh on Twitter