Plattsburg is a city in and the county seat of Clinton County, Missouri and is part of the Kansas City metropolitan area in the western part of the state, within the United States. It developed along the Little Platte River. As of the 2020 census, the city population was 2,222.

Clinton County is a county located in the U.S. state of Missouri and is part of the Kansas City metropolitan area. As of the 2020 U.S. Census, the county had a population of 21,184. Its county seat is Plattsburg. The county was organized January 2, 1833, and named for Governor DeWitt Clinton of New York. The county seat of Plattsburg derives its name from a town of a similar name that is the county seat of Clinton County, New York, which was also named for the Governor.