The gens Plautia, sometimes written Plotia, was a plebeian family at ancient Rome. Members of this gens first appear in history in the middle of the fourth century BC, when Gaius Plautius Proculus obtained the consulship soon after that magistracy was opened to the plebeian order by the Licinio-Sextian rogations. Little is heard of the Plautii from the period of the Samnite Wars down to the late second century BC, but from then to imperial times they regularly held the consulship and other offices of importance. In the first century AD, the emperor Claudius, whose first wife was a member of this family, granted patrician status to one branch of the Plautii.

Marcus Plautius Silvanus was a Roman politician and general active during the Principate. He was consul in 2 BC as the colleague of the emperor Augustus.