Plesetsky District is an administrative district (raion) one of the twenty-one in Arkhangelsk Oblast, Russia. As a municipal division, it is incorporated as Plesetsky Municipal District. It is located in the west of the oblast and borders with Primorsky District in the north, Kholmogorsky District in the northeast, the territories of the town of oblast significance of Mirny and Vinogradovsky District in the east, Shenkursky District in the southeast, Nyandomsky and Kargopolsky Districts in the south, Pudozhsky District of the Republic of Karelia in the west, and with Onezhsky District in the northwest. The area of the district is 27,500 square kilometers (10,600 sq mi). Its administrative center is the urban locality of Plesetsk. Population: 49,077 (2010 Russian census); 58,257 (2002 Census); 83,357 (1989 Soviet census). The population of Plesetsk accounts for 22.5% of the district's total population.

Arkhangelsk Oblast is a federal subject of Russia. It includes the Arctic archipelagos of Franz Josef Land and Novaya Zemlya, as well as the Solovetsky Islands in the White Sea. Arkhangelsk Oblast also has administrative jurisdiction over the Nenets Autonomous Okrug (NAO). Including the NAO, Arkhangelsk Oblast has an area of 587,400 square kilometres (226,800 sq mi), it's the largest of first-level administrative divisions in Europe. Its population was 1,227,626 as of the 2010 Census.