Poindexter & Little was a 19th-century American slave-trading company with operations in Tennessee and Louisiana. The principals were likely Thomas B. Poindexter, John J. Poindexter, Montgomery Little, William Little, Chauncey Little, and Benjamin Little. The Littles were brothers; the Poindexters were most likely brothers but possibly cousins. At the time of the 1860 census, Thomas B. Poindexter had the highest declared net worth of any person who listed their occupation as a slave trader in New Orleans. In 1861 they had a slave depot located at 48 Baronne in New Orleans.

Capt. Montgomery Little, CSA was an American slave trader and a Confederate Army cavalry officer who served in Nathan Bedford Forrest's Escort Company. Little was killed in action during the American Civil War at the Battle of Thompson's Station.