Politics of Hungary takes place in a framework of a parliamentary representative democratic republic. The Prime Minister is the head of government of a pluriform multi-party system, while the President is the head of state and holds a ceremonial position. Executive power is exercised by the government. Legislative power is vested in the parliament; the party system since the last elections is dominated by the conservative Fidesz. The two larger oppositions are Hungarian Socialist Jobbik. Hungary is an independent and constitutional state, a member of the European Union since 2004. Since 1989 Hungary has been a parliamentary republic. Legislative power is exercised by the unicameral National Assembly. Members of the National Assembly are elected for four years; the Economist Intelligence Unit rated Hungary a "flawed democracy" in 2019. The President of the Republic, elected by the National Assembly every five years, has a ceremonial role, but he is nominally the Commander-in-Chief of the armed forces and his powers include the nomination of the Prime Minister, to be elected by a majority of the votes of the Members of Parliament, based on the recommendation made by the President of the Republic.
If the President dies, resigns or is otherwise unable to carry out his duties, the Speaker of the National Assembly becomes acting President. Due to the Hungarian Constitution, based on the post-World War II Basic Law of the Federal Republic of Germany, the Prime Minister has a leading role in the executive branch as he selects Cabinet ministers and has the exclusive right to dismiss them; each cabinet nominee appears before one or more parliamentary committees in consultative open hearings, survive a vote by the Parliament and must be formally approved by the president. In Communist Hungary, the executive branch of the People's Republic of Hungary was represented by the Council of Ministers; the unicameral, 199-member National Assembly is the highest organ of state authority and initiates and approves legislation sponsored by the prime minister. Its members are elected for a four-year term; the election threshold is 5%, but it only applies to the multi-seat constituencies and the compensation seats, not the single-seat constituencies.
A fifteen-member Constitutional Court has power to challenge legislation on grounds of unconstitutionality. This body was last filled on July 2010. Members are elected for a term of twelve years; the President of the Supreme Court of Hungary and the Hungarian civil and penal legal system he leads is independent of the Executive Branch. The Attorney General or Chief Prosecutor of Hungary is fully independent of the Executive Branch, but his status is debated Several ombudsman offices exist in Hungary to protect civil, minority and ecological rights in non-judicial matters, they have held the authority to issue binding decisions since late 2003. The central bank, the Hungarian National Bank was self-governing between 1990–2004, but new legislation gave certain appointment rights to the Executive Branch in November 2004, disputed before the Constitutional Court. Hungary is divided in 19 counties, 23 urban counties*, 1 capital city**. Note: with restructuring and reorganization, this information may change within a governmental period.
Antibe Therapeutics is a Toronto-based pharmaceutical company that develops inflammation-reducing drugs based on gaseous mediator technology. Antibe was founded by John L. Wallace a co-founder of NicOx, the first company to develop drugs utilizing gaseous mediators. In 2015, Antibe acquired a developer and distributor involved in regenerative medicine; the Company is in the final stage of its Phase 2 trials for its first drug. The mechanism of action of Antibe's drugs is the delivery of minute amounts of hydrogen sulfide to sites of inflammation within the human body. Hydrogen sulfide has been shown to enhance the resolution of injury and repair of damage arising from tissue inflammation. Antibe's lead drug, ATB-346, is a hydrogen sulfide-releasing derivative of naproxen, a used non-steroidal anti-inflammatory drug. ATB-346 is being developed to address osteoarthritis, although Antibe intends to broaden its application to rheumatoid arthritis and other diseases now treated with NSAIDs. Unlike standard naproxen, ATB-346 does not induce damage to the gastrointestinal tract.
In May 2014, the company announced that it had completed pre-clinical studies on ATB-346. In late June 2014, following approval from Health Canada, the company announced the first human dosing for Phase I of its human clinical trials. In mid-January 2015, the company announced that clinical trials for its first drug were being suspended due to safety concerns. On March 20, 2018, Antibe Therapeutics announced successful results for Phase 2B Gastrointestinal Safety Study for its lead pain drug, ATB-346. On March 30, 2019, the company launched its final Phase 2B trial for ATB-346. Antibe's products have not yet been approved by the US Drug Administration. Antibe's science advisory board: Andre G. Buret, University of Calgary, Canada Giuseppe Cirino, PhD, University of Naples, Italy Gilberto de Nucci, MD, PhD, University of Sao Paulo, Brazil Peter B. Ernst, DVM, PhD, Professor, UCSD, San Diego, USA Derek Gilroy, PhD, University College, London, UK Richard H. Hunt, MD, Emeritus Professor, McMaster University, Canada Louis Ignarro, PhD Professor, UCLA, Los Angeles, USA - 1998 Nobel Prize Laureate in Medicine Daniel K. Podolsky, MD, University of Texas Southwestern Medical Center, USA William Sessa, PhD, Yale University, USA Philip M. Sherman, MD, University of Toronto, CanadaAntibe's board of directors: Chair - Walt Macnee, Vice Chair, MasterCard International Roderick Flower, Professor Emeritus and The London School of Medicine and Dentistry Dan Legault, CEO, Antibe Therapeutics Amal Khouri, VP Business Development, Knight Therapeutics John L. Wallace, Chief Scientific Officer, Antibe Therapeutics Official website Biotechnology Focus: The Need for a Safer NSAID: Can Antibe Therapeutics Deliver One?
Third International Conference on Medical & Biological Uses of Hydrogen Sulfide
Ottis Elwood Toole was an American drifter and serial killer, convicted of six counts of murder. Like his companion Henry Lee Lucas, Toole made confessions he later recanted, which resulted in murder convictions; the discrediting of the case against Lucas for crimes for which Toole had offered corroborating statements created doubts as to whether either was a genuine serial killer or, as Hugh Aynesworth suggested, both were compliant interviewees whom police used to clear unsolved murders from the books. Toole received two death sentences, he died in his cell from cirrhosis, aged 49. Police attributed the murder of Adam Walsh to Toole on the basis of recanted statements. Lucas had backed Toole's confession to the Walsh murder, claiming he had been in possession of the victim's severed head. Ottis Toole was raised in Jacksonville, Florida. Toole's father was an alcoholic who abandoned him, while his abusive mother would, according to Toole, dress him in girls' clothing and call him Susan. Toole claimed that, as a young child, he was a victim of sexual assault and incest at the hands of many close relatives and acquaintances, including his older sister and a next-door neighbor.
He claimed that his maternal grandmother was a Satanist who exposed him to various Satanic practices and rituals in his youth, including self-mutilation and graverobbing, dubbed him "Devil's Child". Toole claimed. Toole was designated as suffering from mild mental retardation, with an IQ of 75, he suffered from epilepsy, which resulted in frequent grand mal seizures. Throughout Toole's childhood, he ran away from home and slept in abandoned houses, he was sexually aroused by fire. In the documentary Death Diploma, Toole claimed he was forced to have sex with a friend of his father's when he was five years old, he felt he knew he was gay when he was 10, claimed to have had a sexual relationship with a neighborhood boy when he was 12. Toole began visiting gay bars, he claimed to have been a male prostitute as a teenager, became obsessed with gay pornography. Toole claimed to have committed his first murder at the age of 14, when after being propositioned for sex by a traveling salesman, Toole ran over the salesman with his own car.
Toole was first arrested at the age of 17 in August 1965 for loitering. Much information on Toole between 1966 and 1973 is unclear, but authorities believe that he began drifting around the Southwestern United States and that he supported himself by prostitution and panhandling. While living in Nebraska, Toole was one of the prime suspects in the 1974 murder of 24-year-old Patricia Webb. Shortly after, he left Nebraska and settled in Boulder, Colorado. One month he became a prime suspect in the homicide of 31-year-old Ellen Holman, murdered on October 14, 1974. With many accusations against him, Toole headed back to Jacksonville. In early 1975, Toole returned to Jacksonville after drifting and hitch-hiking through the American South. On January 14, 1976, he married a woman 25 years his senior, she left him after discovering his homosexuality. Toole said during an interview. In 1976, Toole met Henry Lee Lucas at a Jacksonville soup kitchen, they soon developed a sexual relationship. Toole claimed to have accompanied Lucas in 1,008 murders, sometimes at the behest of a cult called "The Hands of Death".
Police, discounted the uncorroborated claim of the cult's existence. On January 4, 1982, Toole barricaded 65-year-old George Sonnenberg in a boarding house where he was living in Jacksonville and set the house on fire. Sonnenberg died a week of injuries he sustained in the fire. In April 1983, Toole was arrested for an unrelated arson incident in Jacksonville. Toole confessed to the crime, was sentenced to 20 years in prison. Toole signed a confession stating that he and Sonnenberg had begun a sexual relationship and, after the two had an argument, Toole set Sonnenberg's home on fire. Two months in June, his accomplice Henry Lee Lucas was arrested for unlawful possession of a firearm, it was Lucas began boasting about the murderous rampage orchestrated by the two. At first, Toole had denied involvement but began backing up Lucas's confessions. Lucas backed Toole's confession to the murder of Adam Walsh. Journalist Hugh Aynesworth and others investigated for articles that appeared in The Dallas Times Herald.
It was calculated that Lucas would have had to use his 13-year-old Ford station wagon to cover 11,000 miles in one month i.e. around 370 miles per day, to have committed the crimes police attributed to him. Lucas became regarded as a compliant interviewee, used by police to clear up unsolved murders that he had not been involved in, aided by Toole giving false statements in collaboration. During Toole's trial for murdering George Sonnenberg, Toole claimed that he did not light the home on fire and only signed the confession so he would be extradited back to Jacksonville. On April 28, 1984, a jury sentenced him to death; that year, Toole was found guilty of the February 1983 strangulation murder of a 19-year-old Tallahassee, Florida woman, received a second death sentence. After his incarceration, Toole pled guilty to four more Jacksonville murders in 1991 and received four more life sentences. On October 21, 1983, while imprisoned for two unrelated mur
William P. Roberts was an American politician and diplomat, he was a senior officer of the Confederate States Army who commanded cavalry in the Eastern Theater of the American Civil War. Promoted to Brigadier-General at the age of 23, he was the youngest Confederate general. William Paul Roberts was born July 11, 1841 in Gates County, North Carolina, the son of John S. and Jane Roberts. In 1861, at the age of 19, Roberts enlisted as a private in Company C of the 19th Regiment North Carolina Infantry, which would be designated as the 2nd Regiment NC Cavalry. Having served with distinction during regimental operations in North Carolina, but with no formal military training, he was promoted to second lieutenant on August 30, 1861. On September 13, 1862, Roberts was promoted to First Lieutenant. Roberts' regiment was transferred to Virginia in the fall of the same year and took part in several battles, among them: Battle of Fredericksburg, Battle of Suffolk, Battle of Brandy Station. On November 13, 1863, Roberts was promoted to captain and major before the spring of 1864, when he fought in the North Carolina brigade of William Henry Fitzhugh Lee's division.
He was promoted to colonel in June 1864 and during the Siege of Petersburg, he was given command of the 2nd Regiment NC Cavalry. Roberts led a charge against Union breastworks, overtook the rifle pits and captured several Union soldiers at the Second Battle of Ream's Station on August 25, 1864. On February 23, 1865, Roberts was promoted to brigadier general. According to tradition, General Robert E. Lee presented Roberts with Lee's personal gauntlets in recognition of Roberts' distinguished service. Roberts continued the command of his brigade at the Battle of Five Forks, surrendered at the Battle of Appomattox Court House, on April 9, 1865. Following the War, Roberts returned to Gates County, NC, he entered state politics as the representative for Gates County at the Constitutional Convention in 1875. In 1876, Roberts was elected to the North Carolina legislature, he became the Auditor of North Carolina and served in that capacity from 1880 until 1888. In 1889, President Grover Cleveland appointed him United States Consul for Victoria, British Columbia.
Roberts died in Norfolk, Virginia on March 28, 1910. He is buried in his home county at North Carolina. Galusha Pennypacker, youngest Union Army general List of American Civil War generals Eicher, John H. and David J. Eicher, Civil War High Commands. Stanford: Stanford University Press, 2001. ISBN 978-0-8047-3641-1. Sifakis, Stewart. Who Was Who in the Civil War. New York: Facts On File, 1988. ISBN 978-0-8160-1055-4. Warner, Ezra J. Generals in Gray: Lives of the Confederate Commanders. Baton Rouge: Louisiana State University Press, 1959. ISBN 978-0-8071-0823-9. Web biography at the Wayback Machine
A foreign body is any object originating outside the body of an organism. In machinery, it can mean any unwanted intruding object. Most references to foreign bodies involve propulsion through natural orifices into hollow organs. Foreign bodies can be irritating. If they irritate they will cause scarring, they can bring infection into the body or acquire infectious agents and protect them from the body's immune defenses. They can obstruct passageways either by their size or by the scarring they cause; some can be toxic or generate toxic chemicals from reactions with chemicals produced by the body, as is the case with many examples of ingested metal objects. With sufficient force, a foreign body can become lodged into nearly any tissue. One of the most common locations for a foreign body is the alimentary tract, it is possible for foreign bodies to enter the tract from the rectum. Both children and adults experience problems caused by foreign objects becoming lodged within their bodies. Young children, in particular, are curious and may intentionally put shiny objects, such as coins or button batteries, into their mouths.
They like to insert objects into their ear canals and nostrils. The severity of a foreign body can range from unconcerning to a life-threatening emergency. For example, a coin causes local pressure on the tissue but is not a medical emergency to remove. A button battery, which can be a similar size to a coin, generates hydroxide ions at the anode and causes a chemical burn in two hours. An ingested button battery, stuck in the esophagus is a medical emergency. In 2009, Avolio Luigi and Martucciello Giuseppe showed that although ingested nonmagnetic foreign bodies are to be passed spontaneously without consequence, ingested magnets may attract each other through children's intestinal walls and cause severe damage, such as pressure necrosis, intestinal fistulas and obstruction, it is possible for a foreign body to cause choking. In one study, peanuts were the most common obstruction. In addition to peanuts, hot dogs and latex balloons are serious choking hazards in children that can result in death.
A latex balloon will conform to the shape of the trachea, blocking the airway and making it difficult to expel with the Heimlich maneuver. Foreign body in the bronchi can present as chronic cough. Airborne particles can lodge in the eyes of people at any age; these foreign bodies result in allergies which are either temporary or turn into a chronic allergy. This is evident in the case of dust particles, it is possible for larger objects to lodge in the eye. The most common cause of intraocular foreign bodies is hammering.. Corneal foreign bodies are encountered due to occupational exposure and can be prevented by instituting safety eye-wear at work place. Foreign bodies in the eye affect about 2 per 1,000 people per year. Splinters are common foreign bodies in skin. Staphylococcus aureus infection causes boils to form around them. Tetanus prophylaxis may be appropriate. Foreign bodies in the peritoneum can include retained surgical instruments after abdominal surgery. An intrauterine device can perforate the uterine wall and enter the peritoneum.
Foreign bodies in the peritoneum become contained in a foreign body granuloma. In the rare case of retained ectopic pregnancy, this forms a lithopedion. Foreign bodies can become lodged in other locations: anus or rectum blood vessels or thoracic system ears nose urethra vagina Foreign bodies are common in animals young dogs and cats. Dogs will eat toys and any object that either has food on it or retains the odor of food. Unlike humans, dogs are susceptible to gastrointestinal obstruction due to their ability to swallow large objects and pass them through the esophagus. Foreign bodies most become lodged in the stomach because of the inability to pass through the pyloric sphincter into the jejunum. Symptoms of gastrointestinal obstruction include vomiting, abdominal pain characterized by aggression, acute infection, depression due to dehydration. Treatment of a foreign body is determined by its severity; the amount of time a foreign body is present, location of the object, degree of obstruction, previous health status of the animal and the type of material from which the foreign body is made can all determine the severity of the condition.
Peritonitis results if either intestine has ruptured. Foreign bodies in the stomach can sometimes be removed by endoscopic retrieval or if necessary by gastrotomy. A simple instrument to remove foreign bodies without operation endoscopy is the Hartmann Alligator Forceps; the instrument is manufactured from 8 cm to 1 m length. Foreign bodies in the jejunum are removed by enterotomy. Certain foreign bodies in animals are problematic. Bones or objects with sharp edges may cause tearing of the wall of the esophagus, stomach, or small intestine and lead to peritonitis. Pennies swallowed in large numbers may cause zinc poisoning, which in dogs leads to severe gastroenteritis and hemolytic anemia. Linear foreign bodies can be dangerous. A linear foreign body is a length of string or yarn with a larger object or clump of material at either end. One end is lodged in the stomach or proximal small intestine and the other end continues to travel through the intestines; the material becomes stretched and the intestines may "accordion up" on themselves or be lacerated by it.
This is common in cats who may enjoy playing with a ball of string or yarn. Sometimes the linear foreign body anchors in the mouth by catching
Lt. General Kyaw Swe is the former Minister of Home Affairs of Myanmar, in office from 2016 to 2020, he served as Commander of South-west Command in Pathein, Ayeyarwady Region. In 2017, after the assassination of Ko Ni, a prominent constitutional lawyer and Burmese Muslim, allegations emerged that Kyaw Swe had orchestrated the killing; the assistant secretary of the Home Affairs Ministry, Maung Maung Myint, issued a statement on 1 February 2017, denying the allegations as "rumors."Kyaw Swe was named as the military officer who fabricated charges against Saffron Revolution leader U Gambira on 19 January 2016. The Human Rights Council Working Group on Arbitrary Detention confirmed in their report that U Gambira's arrest and subsequent conviction to be Deprivation of Liberty; the deprivation of liberty of Mr. Gambira was arbitrary, being in “Contravention with Articles 10 and 13 of the Universal Declaration of Human Rights ”. To date, the Myanmar government have not addressed any of The Human Rights Council's recommendations, have denied all findings