The Polyforum Cultural Siqueiros is a cultural, political and social facility located in Mexico City as part of the World Trade Center Mexico City. It was designed and decorated by David Alfaro Siqueiros in the 1960s and hosts the largest mural work in the world called La Marcha de la Humanidad. The building has a theatre, galleries and more, but the main focus is the Forum Universal, which contains the interior portion of Siqueiros' mural work. Visitors can experience the mural while standing on a rotating stage, listening to Siqueiros narrate.

The World Trade Center Mexico City, commonly known by its former name, Hotel de México, is a building complex located in the wealthy neighborhood of Colonia Nápoles in central Mexico City. Its most famous and recognizable feature is the 50-story, 172 metres (564 ft) high Torre WTC, the biggest building in the local area. It is the third tallest building in Mexico City when including antenna, and at its roof height, it stands 218 metres (715 ft).