The Pontifical Academy of Saint Thomas Aquinas is a pontifical academy established on 15 October 1879 by Pope Leo XIII. The academy is one of the pontifical academies housed along with the academies of science at Casina Pio IV in Vatican City, Rome.

Giuseppe Pecci was a Jesuit Thomist theologian whose younger brother, Vincenzo, became Pope Leo XIII and appointed him a cardinal. The Neo-Thomist revival, which Leo XIII and his brother Giuseppe, Cardinal Pecci originated in 1879, remained the leading papal philosophy until Vatican II.