Pope Anastasius II was the bishop of Rome from 24 November 496 to his death. He was an important figure in trying to end the Acacian schism, but his efforts resulted in the Laurentian schism, which followed his death. Anastasius was born in Rome, the son of a priest, and is buried in St. Peter's Basilica.

Pope Liberius was the bishop of Rome from 17 May 352 until his death. According to the Catalogus Liberianus, he was consecrated on 22 May as the successor to Julius I. He is not mentioned as a saint in the Roman Martyrology. That makes him the earliest pontiff not to be venerated as a saint in the Catholic Church and, along with Anastasius II, one of only two popes to be omitted from Catholic sainthood in the first 500 years of church history.