Pope County is the southeasternmost county in the U.S. state of Illinois. According to the 2020 census, it had a population of 3,763, making it the second-least populous county in Illinois. Its county seat is Golconda. The county was organized in 1816 from portions of Gallatin and Johnson counties and named after Nathaniel Pope, a politician and jurist from the Illinois Territory and State of Illinois.

Golconda is a city in and the county seat of Pope County, Illinois, United States, located along the Ohio River. The population was 630 at the 2020 census. Most of the city is part of the Golconda Historic District.