Pope Hormisdas was the bishop of Rome from 20 July 514 to his death. His papacy was dominated by the Acacian schism, started in 484 by Acacius of Constantinople's efforts to placate the Monophysites. His efforts to resolve this schism were successful, and on 28 March 519, the reunion between Constantinople and Rome was ratified in the cathedral of Constantinople before a large crowd.

Frosinone is a comune (municipality) in the Italian region of Lazio, administrative seat of the province of Frosinone. It is about 75 kilometres (47 mi) southeast of Rome, close to the Rome-Naples A1 Motorway. The city is the main city of the Valle Latina, an Italian geographical and historical region that extends from south of Rome to Cassino.