African Americans are an ethnic group of Americans with total or partial ancestry from any of the black racial groups of Africa. The term refers to descendants of enslaved black people who are from the United States. Black and African Americans constitute the third largest racial and ethnic group in the United States. Most African Americans are descendants of enslaved peoples within the boundaries of the present United States. On average, African Americans are of West/Central African and European descent, some have Native American ancestry. According to U. S. Census Bureau data, African immigrants do not self-identify as African American; the overwhelming majority of African immigrants identify instead with their own respective ethnicities. Immigrants from some Caribbean, Central American and South American nations and their descendants may or may not self-identify with the term. African-American history starts in the 16th century, with peoples from West Africa forcibly taken as slaves to Spanish America, in the 17th century with West African slaves taken to English colonies in North America.
After the founding of the United States, black people continued to be enslaved, the last four million black slaves were only liberated after the Civil War in 1865. Due to notions of white supremacy, they were treated as second-class citizens; the Naturalization Act of 1790 limited U. S. citizenship to whites only, only white men of property could vote. These circumstances were changed by Reconstruction, development of the black community, participation in the great military conflicts of the United States, the elimination of racial segregation, the civil rights movement which sought political and social freedom. In 2008, Barack Obama became the first African American to be elected President of the United States; the first African slaves arrived via Santo Domingo to the San Miguel de Gualdape colony, founded by Spanish explorer Lucas Vázquez de Ayllón in 1526. The marriage between Luisa de Abrego, a free black domestic servant from Seville and Miguel Rodríguez, a white Segovian conquistador in 1565 in St. Augustine, is the first known and recorded Christian marriage anywhere in what is now the continental United States.
The ill-fated colony was immediately disrupted by a fight over leadership, during which the slaves revolted and fled the colony to seek refuge among local Native Americans. De Ayllón and many of the colonists died shortly afterwards of an epidemic and the colony was abandoned; the settlers and the slaves who had not escaped returned to Haiti, whence. The first recorded Africans in British North America were "20 and odd negroes" who came to Jamestown, Virginia via Cape Comfort in August 1619 as indentured servants; as English settlers died from harsh conditions and more Africans were brought to work as laborers. An indentured servant would work for several years without wages; the status of indentured servants in early Virginia and Maryland was similar to slavery. Servants could be bought, sold, or leased and they could be physically beaten for disobedience or running away. Unlike slaves, they were freed after their term of service expired or was bought out, their children did not inherit their status, on their release from contract they received "a year's provision of corn, double apparel, tools necessary", a small cash payment called "freedom dues".
Africans could raise crops and cattle to purchase their freedom. They raised families, married other Africans and sometimes intermarried with Native Americans or English settlers. By the 1640s and 1650s, several African families owned farms around Jamestown and some became wealthy by colonial standards and purchased indentured servants of their own. In 1640, the Virginia General Court recorded the earliest documentation of lifetime slavery when they sentenced John Punch, a Negro, to lifetime servitude under his master Hugh Gwyn for running away. In the Spanish Florida some Spanish married or had unions with Pensacola, Creek or African women, both slave and free, their descendants created a mixed-race population of mestizos and mulattos; the Spanish encouraged slaves from the southern British colonies to come to Florida as a refuge, promising freedom in exchange for conversion to Catholicism. King Charles II of Spain issued a royal proclamation freeing all slaves who fled to Spanish Florida and accepted conversion and baptism.
Most went to the area around St. Augustine, but escaped slaves reached Pensacola. St. Augustine had mustered an all-black militia unit defending Spain as early as 1683. One of the Dutch African arrivals, Anthony Johnson, would own one of the first black "slaves", John Casor, resulting from the court ruling of a civil case; the popular conception of a race-based slave system did not develop until the 18th century. The Dutch West India Company introduced slavery in 1625 with the importation of eleven black slaves into New Amsterdam. All the colony's slaves, were freed upon its surrender to the British. Massachusetts was the first British colony to recognize slavery in 1641. In 1662, Virginia passed a law that children of enslaved women took the status of the mother, rather than that of the father, as under English common law; this principle was called partus sequitur ventrum. By an act of 1699, the colony ordered all free blacks deported defining as slaves all people of African descent who remained in the c
National Register of Historic Places listings in Beaufort County, North Carolina
This list includes properties and districts listed on the National Register of Historic Places in Beaufort County, North Carolina. Click the "Map of all coordinates" link to the right to view an online map of all properties and districts with latitude and longitude coordinates in the table below; this National Park Service list is complete through NPS recent listings posted April 12, 2019. National Register of Historic Places listings in North Carolina List of National Historic Landmarks in North Carolina
National Register of Historic Places listings in Davidson County, North Carolina
This list includes properties and districts listed on the National Register of Historic Places in Davidson County, North Carolina. Click the "Map of all coordinates" link to the right to view a Google map of all properties and districts with latitude and longitude coordinates in the table below; this National Park Service list is complete through NPS recent listings posted April 12, 2019. National Register of Historic Places listings in North Carolina List of National Historic Landmarks in North Carolina
A medical device is any device intended to be used for medical purposes. Thus what differentiates. Medical devices benefit patients by helping health care providers diagnose and treat patients and helping patients overcome sickness or disease, improving their quality of life. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assurance before regulating governments allow marketing of the device in their country; as a general rule, as the associated risk of the device increases the amount of testing required to establish safety and efficacy increases. Further, as associated risk increases the potential benefit to the patient must increase. Discovery of what would be considered a medical device by modern standards dates as far back as c. 7000 BC in Baluchistan where Neolithic dentists used flint-tipped drills and bowstrings. Study of archeology and Roman medical literature indicate that many types of medical devices were in widespread use during the time of ancient Rome.
In the United States it wasn't until the Federal Food and Cosmetic Act in 1938 that medical devices were regulated. In 1976, the Medical Device Amendments to the FD&C Act established medical device regulation and oversight as we know it today in the United States. Medical device regulation in Europe as we know it today came into effect in the 1993 by what is collectively known as the Medical Device Directive. On May 26th, 2017 the Medical Device Regulation replaced the MDD. Medical devices vary in both indications for use. Examples range from simple, low-risk devices such as tongue depressors, medical thermometers, disposable gloves, bedpans to complex, high-risk devices that are implanted and sustain life. One example of high-risk devices are those with Embedded software such as pacemakers, which assist in the conduct of medical testing and prostheses. Items as intricate as housings for cochlear implants are manufactured through the deep drawn and shallow drawn manufacturing processes; the design of medical devices constitutes a major segment of the field of biomedical engineering.
The global medical device market reached $209 billion USD in 2006 and was estimated to be between $220 and $250 billion USD in 2013. The United States controls ~40% of the global market followed by Europe and the rest of the world. Although collectively Europe has a larger share, Japan has the second largest country market share; the largest market shares in Europe belong to Germany, Italy and the United Kingdom. The rest of the world comprises regions like Australia, China and Iran; this article discusses what constitutes a medical device in these different regions and throughout the article these regions will be discussed in order of their global market share. A global definition for medical device is difficult to establish because there are numerous regulatory bodies worldwide overseeing the marketing of medical devices. Although these bodies collaborate and discuss the definition in general, there are subtle differences in wording that prevent a global harmonization of the definition of a medical device, thus the appropriate definition of a medical device depends on the region.
A portion of the definition of a medical device is intended to differentiate between medical devices and drugs, as the regulatory requirements of the two are different. Definitions often recognize In vitro diagnostics as a subclass of medical devices and establish accessories as medical devices. Section 201 of the Federal Food Drug & Cosmetic Act defines a device as an "instrument, implement, contrivance, implant, in vitro reagent, or other similar or related article, including a component part, or accessory which is: recognized in the official National Formulary, or the United States Pharmacopoeia, or any supplement to them Intended for use in the diagnosis of disease or other conditions, or in the cure, treatment, or prevention of disease, in man or other animals, or Intended to affect the structure or any function of the body of man or other animals, andwhich does not achieve its primary intended purposes through chemical action within or on the body of man or other animals and, not dependent upon being metabolized for the achievement of its primary intended purposes.
The term'device' does not include software functions excluded pursuant to section 520." According to Article 1 of Council Directive 93/42/EEC, ‘medical device’ means any "instrument, appliance, material or other article, whether used alone or in combination, including the software intended by its manufacturer to be used for diagnostic and/or therapeutic purposes and necessary for its proper application, intended by the manufacturer to be used for human beings for the purpose of: diagnosis, monitoring, treatment or alleviation of disease, monitoring, alleviation of or compensation for an injury or handicap, replacement or modification of the anatomy or of a physiological process, control of conception,and which does not achieve its principal intended action in or on the human body by pharmacological, immunological or metabolic means, but which may be assisted in its function by such means. The New Approach, defined in a European Council Resolution of May 1985, represents an innovative way of technical harmonisation.
It aims to remo
National Register of Historic Places
The National Register of Historic Places is the United States federal government's official list of districts, buildings and objects deemed worthy of preservation for their historical significance. A property listed in the National Register, or located within a National Register Historic District, may qualify for tax incentives derived from the total value of expenses incurred preserving the property; the passage of the National Historic Preservation Act in 1966 established the National Register and the process for adding properties to it. Of the more than one million properties on the National Register, 80,000 are listed individually; the remainder are contributing resources within historic districts. For most of its history the National Register has been administered by the National Park Service, an agency within the United States Department of the Interior, its goals are to help property owners and interest groups, such as the National Trust for Historic Preservation, coordinate and protect historic sites in the United States.
While National Register listings are symbolic, their recognition of significance provides some financial incentive to owners of listed properties. Protection of the property is not guaranteed. During the nomination process, the property is evaluated in terms of the four criteria for inclusion on the National Register of Historic Places; the application of those criteria has been the subject of criticism by academics of history and preservation, as well as the public and politicians. Historic sites outside the country proper, but associated with the United States are listed. Properties can be nominated in a variety of forms, including individual properties, historic districts, multiple property submissions; the Register categorizes general listings into one of five types of properties: district, structure, building, or object. National Register Historic Districts are defined geographical areas consisting of contributing and non-contributing properties; some properties are added automatically to the National Register when they become administered by the National Park Service.
These include National Historic Landmarks, National Historic Sites, National Historical Parks, National Military Parks, National Memorials, some National Monuments. On October 15, 1966, the Historic Preservation Act created the National Register of Historic Places and the corresponding State Historic Preservation Offices; the National Register consisted of the National Historic Landmarks designated before the Register's creation, as well as any other historic sites in the National Park system. Approval of the act, amended in 1980 and 1992, represented the first time the United States had a broad-based historic preservation policy; the 1966 act required those agencies to work in conjunction with the SHPO and an independent federal agency, the Advisory Council on Historic Preservation, to confront adverse effects of federal activities on historic preservation. To administer the newly created National Register of Historic Places, the National Park Service of the U. S. Department of the Interior, with director George B.
Hartzog Jr. established an administrative division named the Office of Archeology and Historic Preservation. Hartzog charged OAHP with creating the National Register program mandated by the 1966 law. Ernest Connally was the Office's first director. Within OAHP new divisions were created to deal with the National Register; the division administered several existing programs, including the Historic Sites Survey and the Historic American Buildings Survey, as well as the new National Register and Historic Preservation Fund. The first official Keeper of the Register was an architectural historian. During the Register's earliest years in the late 1960s and early 1970s, organization was lax and SHPOs were small and underfunded. However, funds were still being supplied for the Historic Preservation Fund to provide matching grants-in-aid to listed property owners, first for house museums and institutional buildings, but for commercial structures as well. A few years in 1979, the NPS history programs affiliated with both the U.
S. National Parks system and the National Register were categorized formally into two "Assistant Directorates." Established were the Assistant Directorate for Archeology and Historic Preservation and the Assistant Directorate for Park Historic Preservation. From 1978 until 1981, the main agency for the National Register was the Heritage Conservation and Recreation Service of the United States Department of the Interior. In February 1983, the two assistant directorates were merged to promote efficiency and recognize the interdependency of their programs. Jerry L. Rogers was selected to direct this newly merged associate directorate, he was described as a skilled administrator, sensitive to the need for the NPS to work with SHPOs, local governments. Although not described in detail in the 1966 act, SHPOs became integral to the process of listing properties on the National Register; the 1980 amendments of the 1966 law further defined the responsibilities of SHPOs concerning the National Register.
Several 1992 amendments of the NHPA added a category to the National Register, known as Traditional Cultural Properties: those properties associated with Native American or Hawaiian groups
National Register of Historic Places listings in Camden County, North Carolina
This list includes properties and districts listed on the National Register of Historic Places in Camden County, North Carolina. Click the "Map of all coordinates" link to the right to view an online map of all properties and districts with latitude and longitude coordinates in the table below; this National Park Service list is complete through NPS recent listings posted April 12, 2019. National Register of Historic Places listings in North Carolina List of National Historic Landmarks in North Carolina
American Civil War
The American Civil War was a war fought in the United States from 1861 to 1865, between the North and the South. The Civil War is the most studied and written about episode in U. S. history. As a result of the long-standing controversy over the enslavement of black people, war broke out in April 1861 when secessionist forces attacked Fort Sumter in South Carolina shortly after Abraham Lincoln had been inaugurated as the President of the United States; the loyalists of the Union in the North proclaimed support for the Constitution. They faced secessionists of the Confederate States in the South, who advocated for states' rights to uphold slavery. Among the 34 U. S. states in February 1861, secessionist partisans in seven Southern slave states declared state secessions from the country and unveiled their defiant formation of a Confederate States of America in rebellion against the U. S. Constitutional government; the Confederacy grew to control over half the territory in eleven states, it claimed the additional states of Kentucky and Missouri by assertions from exiled native secessionists without territory or population.
These were given full representation in the Confederate Congress throughout the Civil War. The two remaining slave holding states of Delaware and Maryland were invited to join the Confederacy, but nothing substantial developed; the Confederate States was never diplomatically recognized by the government of the United States or by that of any foreign country. The states that remained loyal to the U. S. were known as the Union. The Union and the Confederacy raised volunteer and conscription armies that fought in the South over the course of four years. Intense combat left 620,000 to 750,000 people dead, more than the number of U. S. military deaths in all other wars combined. The war ended when General Robert E. Lee surrendered to General Ulysses S. Grant at the Battle of Appomattox Court House. Confederate generals throughout the southern states followed suit. Much of the South's infrastructure was destroyed the transportation systems; the Confederacy collapsed, slavery was abolished, four million black slaves were freed.
During the Reconstruction Era that followed the war, national unity was restored, the national government expanded its power, civil rights were granted to freed black slaves through amendments to the Constitution and federal legislation. In the 1860 presidential election, led by Abraham Lincoln, supported banning slavery in all the U. S. territories. The Southern states viewed this as a violation of their constitutional rights and as the first step in a grander Republican plan to abolish slavery; the three pro-Union candidates together received an overwhelming 82% majority of the votes cast nationally: Republican Lincoln's votes centered in the north, Democrat Stephen A. Douglas' votes were distributed nationally and Constitutional Unionist John Bell's votes centered in Tennessee and Virginia; the Republican Party, dominant in the North, secured a plurality of the popular votes and a majority of the electoral votes nationally. He was the first Republican Party candidate to win the presidency.
However, before his inauguration, seven slave states with cotton-based economies declared secession and formed the Confederacy. The first six to declare secession had the highest proportions of slaves in their populations, with an average of 49 percent. Of those states whose legislatures resolved for secession, the first seven voted with split majorities for unionist candidates Douglas and Bell, or with sizable minorities for those unionists. Of these, only Texas held a referendum on secession. Eight remaining slave states continued to reject calls for secession. Outgoing Democratic President James Buchanan and the incoming Republicans rejected secession as illegal. Lincoln's March 4, 1861, inaugural address declared that his administration would not initiate a civil war. Speaking directly to the "Southern States", he attempted to calm their fears of any threats to slavery, reaffirming, "I have no purpose, directly or indirectly to interfere with the institution of slavery in the United States where it exists.
I believe I have no lawful right to do so, I have no inclination to do so." After Confederate forces seized numerous federal forts within territory claimed by the Confederacy, efforts at compromise failed and both sides prepared for war. The Confederates assumed that European countries were so dependent on "King Cotton" that they would intervene, but none did, none recognized the new Confederate States of America. Hostilities began on April 1861, when Confederate forces fired upon Fort Sumter. While in the Western Theater the Union made significant permanent gains, in the Eastern Theater, the battle was inconclusive during 1861–1862. In September 1862, Lincoln issued the Emancipation Proclamation, which made ending slavery a war goal. To the west, by summer 1862 the Union destroyed the Confederate river navy much of its western armies, seized New Orleans; the successful 1863 Union siege of Vicksburg split the Confederacy in two at the Mississippi River. In 1863, Robert E. Lee's Confederate incursion north ended at the Battle of Gettysburg.
Western successes led to Ulysses S. Grant's command of all Union armies in 1864. Inflicting an ever-tightening naval blockade of Confederate ports, the Union marshaled the resources and manpower to attack the Confederacy from all directions, leading to the fall of Atlanta to William T. Sherman and his march to th