Pope Zephyrinus was the bishop of Rome from 199 to his death on 20 December 217. He was born in Rome, and succeeded Victor I. Upon his death on 20 December 217, he was succeeded by his principal advisor, Callixtus I. He is known for combating heresies and defending the divinity of Christ.

Pope Victor I was a Roman African prelate of the Catholic Church who served as Bishop of Rome in the late second century. The dates of his tenure are uncertain, but one source states he became pope in 189 and gives the year of his death as 199. He was born in the Roman Province of Africa—probably in Leptis Magna. He was later considered a saint. His feast day is celebrated on 28 July as "St Victor I, Pope and Martyr". He was of Berber origin.