Port Royal is a town on Port Royal Island in Beaufort County, South Carolina, United States. The population was 14,220 at the 2020 census. It is part of the Hilton Head Island–Bluffton metropolitan area. Port Royal is home to Marine Corps Recruit Depot Parris Island and United States Naval Hospital Beaufort.

Beaufort County is a county in the U.S. state of South Carolina. As of the 2020 census, its population was 187,117. Its county seat is Beaufort and its largest community is Hilton Head Island.