The Port of Ploče is a seaport in Ploče, Croatia, near the mouth of the Neretva river on the Adriatic Sea coast. It was formally opened in 1945 after a railway was built as a supply route to connect the site with industrial facilities in the Sarajevo and Mostar areas of Bosnia and Herzegovina, which was then part of Yugoslavia. As of 2010, it ranked as the second largest cargo port in Croatia—after the Port of Rijeka—with a cargo throughput of 4.5 million tonnes, consisting mostly of general cargo and bulk cargo, including 20,420 TEU Containers. In 2008, the Port of Ploče recorded 2,555 ship arrivals. It is managed by the Port of Ploče Authority.

Ploče is a town and seaport in the Dubrovnik-Neretva County of Croatia.