Portland Union Station is a train station in Portland, Oregon, United States, situated near the western shore of the Willamette River in Old Town Chinatown. It serves as an intermediate stop for Amtrak's Cascades and Coast Starlight routes and, along with King Street Station in Seattle, is one of two western termini of the Empire Builder. The station is a major transport hub for the Portland metropolitan area with connections to MAX Light Rail, the Portland Streetcar, and local and intercity bus services. The station building contains Wilf's Restaurant & Bar on the ground level and offices on the upper floors. It also has Amtrak's first Metropolitan Lounge on the West Coast, which is reserved for first-class sleeping car and business-class passengers.

Old Town Chinatown is the official Chinatown of the northwest section of Portland, Oregon. The Willamette River forms its eastern boundary, separating it from the Lloyd District and the Kerns and Buckman neighborhoods. It includes the Portland Skidmore/Old Town Historic District and the Portland New Chinatown/Japantown Historic District, which are listed on the National Register of Historic Places. It has been referred to as the "skid row" of Portland.