Frederick Augustus Conrad Muhlenberg is a portrait of 1790 by Joseph Wright, now in the collection of the National Portrait Gallery. It depicts Muhlenberg in his position as the first Speaker of the U.S. House of Representatives.

Joseph Wright was an American portrait painter and sculptor. He painted life portraits of George Washington and Benjamin Franklin, and was a designer of early U.S. coinage. Wright was President Washington's original choice for Chief Engraver of the U.S. Mint, but died at age 37, before being confirmed to that position.