Potter County is a county located in the U.S. state of Texas. As of the 2020 census, its population was 118,525. Its county seat is Amarillo. The county was created in 1876 and organized in 1887. It is named for Robert Potter, a politician, signer of the Texas Declaration of Independence, and the Texas Secretary of the Navy. Potter County is included in the Amarillo metropolitan area.

Amarillo is a city in the U.S. state of Texas and the seat of Potter County. It is the 14th-most populous city in Texas and the most populous city in the Texas Panhandle. A portion of the city extends into Randall County. The estimated population of Amarillo was 200,393 as of April 1, 2020, comprising nearly half of the population of the panhandle. The Amarillo metropolitan area had an estimated population of 308,297 as of 2020.