Potton was a railway station on the Varsity Line which served the small town of the same name in Bedfordshire. Opened in 1857 as part of Sir William Peel's Sandy and Potton Railway, the station was initially situated further south near the Biggleswade Road. Upon being taken over by the Bedford and Cambridge Railway in 1862 a new station was opened which remained in service for over one hundred years before closing in 1968. The station building has survived and is now a private house.

The Varsity Line was the main railway line that linked the English university cities of Oxford and Cambridge, operated by the London and North Western Railway.