"Predators and Prey" is the fifth story arc that spreads from the twenty-first to the twenty-fifth issue of the Buffy the Vampire Slayer Season Eight series of comic books, a continuation of the television series of the same name. The arc is written by Jane Espenson, Steven S. DeKnight, Drew Z. Greenberg, Jim Krueger, Doug Petrie.

Buffy the Vampire Slayer Season Eight is a comic book series published by Dark Horse Comics from 2007 to 2011. The series serves as a canonical continuation of the television series Buffy the Vampire Slayer, and follows the events of that show's final televised season. It is produced by Joss Whedon, who wrote or co-wrote three of the series arcs and several one-shot stories. The series was followed by Season Nine in 2011.