The best known cultural archaeological discoveries from the prehistoric period on the territory of modern-day Serbia are the Starčevo and Vinča cultures dating back to 6400–6200 BC.

The Starčevo culture is an archaeological culture of Southeastern Europe, dating to the Neolithic period between c. 6200 and 4500 BCE. It originates in the spread of the Neolithic package of peoples and technological innovations including farming and ceramics from Anatolia to the area of Sesklo. The Starčevo culture marks its spread to the inland Balkan peninsula as the Cardial ware culture did along the Adriatic coastline. It forms part of the wider Starčevo–Körös–Criş culture which gave rise to the central European Linear Pottery culture c. 700 years after the initial spread of Neolithic farmers towards the northern Balkans.