Prentice Women's Hospital is an acute care women's hospital located adjacent to both Northwestern Memorial and the Lurie Children's Hospital, in Chicago, Illinois, United States. Prentice Women's Hospital is a member of Northwestern Medicine and serves as a teaching hospital for the Northwestern University Feinberg School of Medicine. The hospital provides tertiary-level obstetric, gynecological, and neonatal care to patients from the entire region. The hospital has 256 beds, with 86 AAP verified level III neonatal intensive care unit beds, 32 labor and delivery beds, 86 healthy bassinets, and 10 operating rooms. The hospital is directly attached to the Lurie Children's Hospital via skybridge because Lurie physicians provide care on Prentice's neonatal intensive care units.

The Prentice Women's Hospital and Maternity Center was a hospital on the Downtown Chicago campus of Northwestern University's Northwestern Memorial Hospital in the Streeterville district of Chicago's Near North Side.