Prescot is a town and civil parish within the Metropolitan Borough of Knowsley in Merseyside, United Kingdom. It lies about eight miles (13 km) to the east of Liverpool city centre. At the 2001 Census, the civil parish population was 11,184. The population of the larger Prescot East and West wards at the 2011 census totalled 14,139. Prescot marks the beginning of the A58 road which runs through to Wetherby, near Leeds in West Yorkshire. The town is served by Prescot railway station and Eccleston Park railway station in neighbouring Eccleston.

The Metropolitan Borough of Knowsley is a metropolitan borough in Merseyside, North West England. It covers several towns and villages, including Kirkby, Prescot, Huyton, Whiston, Halewood, Cronton and Stockbridge Village; Kirkby, Huyton, and Prescot being the major commercial centres. It takes its name from the village of Knowsley, though its headquarters are in Huyton. It forms part of the wider Liverpool City Region.