Prescott Sheldon Bush Sr. was an American banker and Republican Party politician. After working as a Wall Street executive investment banker, he represented Connecticut in the United States Senate from 1952 to 1963. A member of the Bush family, he was the father of President George H. W. Bush, and the paternal grandfather of President George W. Bush and Florida Governor Jeb Bush.

James Smith Bush was an American attorney, Episcopal priest, religious writer, and an ancestor of the Bush political family. He was the father of business magnate Samuel P. Bush, grandfather of former U.S. Senator Prescott Bush, great-grandfather of former U.S. President George H. W. Bush and great-great-grandfather of former Texas Governor and President George W. Bush and former Florida Governor Jeb Bush.