President of the Quorum of the Twelve Apostles is a priesthood calling in the Church of Jesus Christ of Latter-day Saints. Normally, the president of the Quorum of the Twelve is the most senior apostle in the church, aside from the president of the church. When the president of the church dies, it is the president of the Quorum of the Twelve who becomes the new church president. The calling of President of the Twelve has been held by 27 men. 16 Quorum Presidents have subsequently become President of the Church. Since January 2018, Dallin H. Oaks has been the President of the Quorum of the Twelve. Since Oaks is also first counselor in the First Presidency, M. Russell Ballard served as acting president until his death on November 12, 2023. Jeffrey R. Holland became the new acting president on November 15, 2023.

In the Church of Jesus Christ of Latter-day Saints, the Quorum of the Twelve Apostles is one of the governing bodies in the church hierarchy. Members of the Quorum of the Twelve Apostles are apostles, with the calling to be prophets, seers, and revelators, evangelical ambassadors, and special witnesses of Jesus Christ.