Price's Missouri Expedition, also known as Price's Raid or Price's Missouri Raid, was an unsuccessful Confederate cavalry raid through Arkansas, Missouri, and Kansas in the Trans-Mississippi Theater of the American Civil War. Led by Confederate Major General Sterling Price, the campaign aimed to recapture Missouri and renew the Confederate initiative in the larger conflict.

The trans-Mississippi theater of the American Civil War was the scene of the major military operations west of the Mississippi River. The area is often thought of as excluding the states and territories bordering the Pacific Ocean, which formed the Pacific coast theater of the American Civil War (1861–1865).