The Prime Minister of the Lao People's Democratic Republic, formerly the chairman of the Council of Government of the Lao People's Democratic Republic, is the head of government of Laos. The highest position in the government, they direct the country's executive branch. The prime minister is accountable to the president, the National Assembly and the country's only legal party: the Lao People's Revolutionary Party (LPRP). The current prime minister is Sonexay Siphandone, who was elected in 2022.

The politics of the Lao People's Democratic Republic takes place in the framework of a one-party parliamentary socialist republic. The only legal political party is the Lao People's Revolutionary Party (LPRP). The head of state is President Thongloun Sisoulith, who is also the LPRP general secretary, making him the supreme leader of Laos. The head of government is Prime Minister Sonexay Siphandone.