The prime minister of Slovakia, officially the Chairman of the government of the Slovak Republic, commonly referred to in Slovakia as Predseda vlády or informally as Premiér, is the head of the government of the Slovak Republic. Officially, the officeholder is the third-highest constitutional official in Slovakia after the President of the Republic (appointer) and Chairman of the National Council; in practice, the appointee is the country's leading political figure.

The Government of the Slovak Republic exercises executive authority in Slovakia. It is led by the Prime Minister of Slovakia, who is nominated by the President of Slovakia, and is usually the leader of majority party or of majority coalition after an election to the National Council of the Slovak Republic. The Cabinet appointed by the president on recommendation of the prime minister must gain a vote of confidence in the National Council.