The prime minister of Tunisia is the head of the executive branch of the government of Tunisia. The prime minister directs the executive branch along with the president and, together with the prime minister's cabinet, is accountable to the Assembly of the Representatives of the People, to the prime minister's political party and, ultimately, to the electorate for the policies and actions of the executive and the legislature.

The politics of Tunisia takes place within the framework of a unitary semi-presidential representative democratic republic, with a president serving as head of state, prime minister as head of government, a unicameral legislature and a court system influenced by French civil law. Between 1956 and 2011, Tunisia operated as a de facto one-party state, with politics dominated by the secular Constitutional Democratic Rally (RCD) under former presidents Habib Bourguiba and then Zine el Abidine Ben Ali. However, in 2011 a national uprising led to the ousting of Ben Ali and the dismantling of the RCD, paving the way for a multi-party democracy. October 2014 saw the first democratic parliamentary elections since the 2011 revolution, resulting in a win by the secularist Nidaa Tounes party with 85 seats in the 217-member assembly.