A prince-bishop is a bishop who is also the civil ruler of some secular principality and sovereignty, as opposed to Prince of the Church itself, a title associated with cardinals. Since 1951, the sole extant prince-bishop has been the Bishop of Urgell, Catalonia, who has remained ex officio one of two co-princes of Andorra, along with the French president.

Prince of the Holy Roman Empire was a title attributed to a hereditary ruler, nobleman or prelate recognised as such by the Holy Roman Emperor.