Prince Leopold (1813–1817) was a British Thoroughbred racehorse and winner of the 1816 Epsom Derby. Prince Leopold was bred by the Duke of York and raced as a three and four-year-old. The bay colt had an unruly temperament, and was castrated at the end of the 1817 racing season in an attempt to improve his behavior, but he died shortly after the procedure.

The Derby Stakes, also known as the Derby or the Epsom Derby, is a Group 1 flat horse race in England open to three-year-old colts and fillies. It is run at Epsom Downs Racecourse in Surrey on the first Saturday of June each year, over a distance of one mile, four furlongs and 10 yards, or about 1½ miles. It was first run in 1780.