Marko Mrnjavčević was the de jure Serbian king from 1371 to 1395, while he was the de facto ruler of territory in western Macedonia centered on the town of Prilep. He is known as Prince Marko and King Marko in South Slavic oral tradition, in which he has become a major character during the period of Ottoman rule over the Balkans. Marko's father, King Vukašin, was co-ruler with Serbian Tsar Stefan Uroš V, whose reign was characterised by weakening central authority and the gradual disintegration of the Serbian Empire. Vukašin's holdings included lands in north-western Macedonia and Kosovo. In 1370 or 1371, he crowned Marko "young king"; this title included the possibility that Marko would succeed the childless Uroš on the Serbian throne.

Macedonia is a geographical and historical region of the Balkan Peninsula in Southeast Europe. Its boundaries have changed considerably over time; however, it came to be defined as the modern geographical region by the mid-19th century. Today the region is considered to include parts of six Balkan countries: all of North Macedonia, large parts of Greece and Bulgaria, and smaller parts of Albania, Serbia, and Kosovo. It covers approximately 67,000 square kilometres (25,869 sq mi) and has a population of around five million. Greek Macedonia comprises about half of Macedonia's area and population.