Prince of Wales–Hyder Census Area is a census area located in the U.S. state of Alaska. As of the 2020 census, the population was 5,753, up from 5,559 in 2010. It is part of the unorganized borough and therefore has no borough seat. Its largest communities are Metlakatla and Craig. It was formerly part of the Census Bureau's Prince of Wales–Outer Ketchikan Census Area, but the name was changed in 2008 after most of the Outer Ketchikan was lost to annexation by the Ketchikan Gateway Borough.

The Unorganized Borough is composed of the portions of the U.S. state of Alaska which are not contained in any of its 19 organized boroughs. While referred to as the "Unorganized Borough", it is not a borough itself, as it forgoes that level of government structure. It encompasses nearly half of Alaska's land area, 323,440 square miles (837,700 km2), and, as of the 2020 U.S. Census, it had a population of 77,157, which was 10.52% of the population of the state. The largest communities in the Unorganized Borough are the cities of Bethel, Unalaska, and Valdez.