Alexandra of Hanover and Cumberland was the wife of Frederick Francis IV, Grand Duke of Mecklenburg-Schwerin. As such, she was the last consort of Mecklenburg-Schwerin from their marriage on 7 June 1904 until the Grand Duke abdicated on 14 November 1918, following the German Revolution of 1918. Alexandra was the daughter of Ernest Augustus, Crown Prince of Hanover, and Princess Thyra of Denmark.

Frederick Francis III was the penultimate Grand Duke of Mecklenburg-Schwerin.