Alexandra of Hanover and Cumberland was the wife of Frederick Francis IV, Grand Duke of Mecklenburg-Schwerin. As such, she was the last consort of Mecklenburg-Schwerin from their marriage on 7 June 1904 until the Grand Duke abdicated on 14 November 1918, following the German Revolution of 1918. Alexandra was the daughter of Ernest Augustus, Crown Prince of Hanover, and Princess Thyra of Denmark.

Frederick Francis IV was the last Grand Duke of Mecklenburg-Schwerin and regent of Mecklenburg-Strelitz. He inherited the throne when he was fifteen years old in 1897 and was forced to renounce it in 1918.