Princess Margaret of Denmark was a Danish princess by birth and a princess of Bourbon-Parma as the wife of Prince René of Bourbon-Parma. She was the youngest grandchild of Christian IX of Denmark and Queen Louise.

Prince René of Bourbon-Parma was the seventh surviving son of Robert I, Duke of Parma, and his second wife, Infanta Maria Antonia of Portugal. In 1921, he married Princess Margaret of Denmark. They had four children including Anne, the wife of Michael I, former King of Romania.