Proactiv is an American brand of skin-care products developed by two American dermatologists, Katie Rodan and Kathy A. Fields, and launched in 1995 by Guthy-Renker, a California-based direct marketing company, that was endorsed by famous celebrities The range includes moisturizers, body washes and treatment products, but the brand is known for its three-step anti-acne Solutions 3-step routine consisting of a BPO cleanser, glycolic toner and treatment lotion. Proactiv+, a reformulation of the three-step kit, was introduced in 2013, and in 2017, ProactivMD launches powered by Adapalene.

Guthy-Renker is a California-based direct-response marketing company that sells health and beauty products directly to consumers through infomercials, television ads, direct mail, telemarketing, e-mail marketing, and the Internet. Many of its products are endorsed by celebrities including actresses and musicians