The Professional Football League of America (PFLA) was an American football minor league that operated in the Midwest region of the United States from 1965 through 1967. With franchises based in the Midwest, the league played three seasons before merging some teams into the Continental Football League.

The Quad City Raiders were a professional American football team based in the Quad Cities region, which includes Rock Island, Illinois and neighboring Davenport, Iowa. In 1965, the Raiders joined the Professional Football League of America (PFLA) as the Rock Island Raiders became charter members. The Quad City Raiders remained in the PFLA until its merger with the Continental Football League in 1968, with the franchise evolving to become the Las Vegas Cowboys.