Prophecy is a 1979 American science fiction monster horror-thriller film directed by John Frankenheimer and written by David Seltzer. It stars Robert Foxworth, Talia Shire and Armand Assante. Set along the Androscoggin or Ossipee River, the film follows an environmental agent and his wife filing a report on a paper mill in the river, not knowing that the paper mill's waste has polluted the river, causing mutations to man and beast alike. One of these animals, a local bear, runs amok in the wilderness.

David Seltzer is an American screenwriter, producer and director, perhaps best known for writing the screenplays for The Omen (1976) and Bird on a Wire (1990). As writer-director, Seltzer's credits include the 1986 teen tragi-comedy Lucas starring Corey Haim, Charlie Sheen and Winona Ryder, the 1988 comedy Punchline starring Sally Field and Tom Hanks, and 1992's Shining Through starring Melanie Griffith and Michael Douglas.